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From One of Our Readers… About Remdesivir…

By Fuzzyone | August 17, 2020 | CDC, Drug Cartels, Food & Drug Admin (FDA), Health

The following is a letter sent to Noxandfriends, from a biochemist, E.J.Ledet, who did some looking into Remdisivir.. We will let you make up your own mind on this without commenting…

Subject: Remdesivir is a ligand ionophore transporter of zinc

Comment: We believe that HCQ is in direct competition with Remdesivir and that Gilead, Big Pharma has put a lot of $$ pressure on MDs, Medical Journals, Press, Academia, NIH, CDC to discredit HCQ after 65 yrs of safe use as a malaria drug and 40 years of safe use to treat lupus and some forms of arthritis.

Gilead contributes $$$ to the income of 20% of NIH Board MDs and Fauci heads NIH. Gilead also funds a great deal of $$$ to Academia Medical research and $$ to Medical journal publishers. The ZInc15 Ligand database, a database containing 230 million zinc ligand/ionophores for sale as potential drugs to various pharmaceutical companies and has 750 million viewable zinc ionophores is funded by NIH of which Fauci is the head.

My recent sleuthing into Remdesivir using the Pharmacology Database and comparing homologue/analogue organic structure similarities for binding sites of zinc, show that Remdesivir is also a zinc ligand/ ionophore (carrier molecule). Gilead has not shared that information with the public but I’m quite sure that Gilead Pharmacology Chemist are very aware that Remdesivir is a ligand ionophore for zinc and can help transport zinc across cell membranes to interfere with viral RNA RdRp enzyme and prevent further virion reproduction just like its HCQ competitor. Gilead synthesized Remdesivir so that it mimics ATP which is critical for RNA reproduction . Since Remdesivir’s organic structure is slightly different from ATP, incorporation of its biological transformed homologue or its synthetic structure depicted below by the virus interrupts RNA transcription and produces pieces of viral RNA which can not be reassembled to make new viruses.

I believe that Gilead is not promoting/touting Remdesivir as a zinc ionophore because its afraid of losing out to HCQ which is one hundred times less expensive since its patent ran out many years ago and is currently produced in 12 different pharmacology labs in India.

Gilead has spent $ hundreds of millions in research/marketing/propaganda, and Gilead stands to lose $ Billions in sales as one 5 day treatment costs $2340.

I’m attaching a graphic which shows the chemical structures of zinc ionophores. Adenosine, ATP, Quercetin, HCQ, and Remdesivir. Zn is shown bound to Hydroxyl (OH) molecules which are present in every structure on the below Structures.

https://www.dropbox.com/s/moeqo17fqpkbhr4/PastedGraphic-1.png?dl=0

Cost Comparison: Remdesivir $2340; HCQ $25-30; Quercetin $5.40

https://www.dropbox.com/s/12jo6hosgptlwkp/PastedGraphic-3.tiff?dl=0

E.J. Ledet

Biochemist

Bellingham WA

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